As a biomedical engineer who specializes in data science, Miller is pioneering cutting-edge technologies in computational medicine to understand and diagnose neurodegenerative diseases.

He has received numerous awards for his work, including the national Institute of Electrical and Electronics Engineers (IEEE) Biomedical Engineering Thesis Award in 1982, the Johns Hopkins Paul Ehrlich Graduate Student Thesis Award in 1983, and the National Science Foundation (NSF) Presidential Young Investigator Award in 1986.

He was named an inaugural Johns Hopkins University Gilman Scholar in 2011 for demonstrating a distinguished record of research, teaching, and service.

He is an elected Fellow of the American Institute for Medical and Biological Engineering, the Institute of Electrical and Electronics Engineers, and the Biomedical Engineering Society.

He was elected as member of the Euorpean Academy of Engineering in 2023.